Stiff Person Syndrome
SPS is labeled as a rare disease. Muscle spasms can be so violent they can dislocate joints and even break bones.
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A Treatment Update and New Directions Authors Juan Fernando Ortiz 1 Mohammad R Ghani 1 Álvaro Morillo Cox 2 Willians Tambo 3 Farah Bashir 4 Martín Wirth 3 Gustavo Moya 5 Affiliations 1 Neurology California Institute of Behavioral Neurosciences Psychology Fairfield USA.
. Stiff person syndrome SPS is an autoimmune neurological disorder. But more people are affected than reported due to misdiagnoses. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility.
Myoclonus is a general term used to describe the sudden involuntary jerking of a muscle or group of muscles caused by muscle contractions positive myoclonus or. Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord. Certain cancers including breast lung kidney thyroid colon and Hodgkins lymphoma.
Stiff person syndrome is more likely seen in people with certain types of diseases including. Spasms can generate enough force to fracture bone. Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease.
Like other types of neurological disorders SPS affects your brain and spinal cord central nervous system. Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety. The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities.
SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms. SPS occurs in about one in a. Stiff person syndrome SPS is a neurological disease with autoimmune features.
Chronic pain impaired mobility and lumbar hyperlordosis are common symptoms. Affected individuals also develop involvement of the brainstem which can cause myoclonus. Tests for diagnosing stiff person syndrome may include the following.
Serum anti-GAD glutamic acid decarboxylase 65 antibody serum amphiphysin antibody several other serum autoantibodies hemoglobin A1c and vitamin levels lumbar puncture MRI of the brain and spine neurophysiological studies. Stiff-person syndrome also known as stiff-man syndrome is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness. Jerking stiff-person syndrome is characterized by muscles stiffness and spasms usually affecting the legs.
Autoimmune disorders including diabetes thyroiditis vitiligo and pernicious anemia. Stiff Person Syndrome An autoimmune and neurological disorder that causes rigidity and spasms in the trunk and limbs Symptoms include stiffening in the torso and limbs along with episodes of severe muscle spasms Medications and immunotherapy maybe prescribed with aqua occupational and.
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